2UYM: Crystal structure of KSP in complex with ADP and thiophene containing inhibitor 37

PDB ID: 2UYMDownload
MMDB ID: 46814
PDB Deposition Date: 2007/4/10
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.11  Å
Source Organism:
Similar Structures:
Biological Unit for 2UYM: monomeric; determined by author and by software (PQS)
Molecular Components in 2UYM
Label Count Molecule
Protein (1 molecule)
1
Kinesin-like Protein Kif11
(Gene symbol: KIF11)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
ADENOSINE-5'-DIPHOSPHATEADENOSINE-5'-DIPHOSPHATE
2
1
MAGNESIUM IONMAGNESIUM ION
3
1
N,N-DIETHYL-5,5-DIMETHYL-2-[(2-THIENYLCARBONYL)AMINO]-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDEN,N-DIETHYL-5,5-DIMETHYL-2-[(2-THIENYLCARBONYL)AMINO]-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303