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2VKU:
4,4'-Dihydroxybenzophenone Mimics Sterol Substrate in the Binding Site of Sterol 14alpha-Demethylase (CYP51) in the X-ray Structure of the Complex
PDB ID:
2VKU
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MMDB ID:
63266
PDB Deposition Date:
2007/12/29
Updated in MMDB:
2023/12
Experimental Method:
x-ray diffraction
Resolution:
1.95 Å
Source Organism:
Mycobacterium tuberculosis H37Rv
Similar Structures:
VAST+
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Biological Unit for 2VKU: monomeric; determined by author and by software (PQS)
Molecular Components in 2VKU
Label
Count
Molecule
Protein (1 molecule)
A
1
Cytochrome P450 51
Chemicals and Non-standard biopolymers (11 molecules)
1
4
bis(4-hydroxyphenyl)methanone
2
1
PROTOPORPHYRIN IX CONTAINING FE
3
6
SULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303