2VUM: Alpha-amanitin inhibited complete RNA polymerase II elongation complex

PDB ID: 2VUMDownload
MMDB ID: 163890
PDB Deposition Date: 2008/5/27
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 3.4  Å
Source Organism:
Amanita phalloides▼
Similar Structures:
Biological Unit for 2VUM: hexadecameric; determined by author and by software (PISA)
Molecular Components in 2VUM
Label Count Molecule
Proteins (13 molecules)
1
DNA-directed RNA Polymerase II Subunit Rpb1
Molecule annotation
1
DNA-directed RNA Polymerase II Subunit Rpb2
Molecule annotation
1
DNA-directed RNA Polymerase II Subunit Rpb3
Molecule annotation
1
DNA-directed RNA Polymerase II Subunit Rpb4
Molecule annotation
1
DNA-directed RNA Polymerases I, II, and III Subunit Rpabc1
Molecule annotation
1
DNA-directed RNA Polymerases I, II, and III Subunit Rpabc2
Molecule annotation
1
DNA-directed RNA Polymerase II Subunit Rpb7
Molecule annotation
1
DNA-directed RNA Polymerases I, II, and III Subunit Rpabc3
Molecule annotation
1
DNA-directed RNA Polymerase II Subunit Rpb9
Molecule annotation
1
DNA-directed RNA Polymerases I, II, and III Subunit Rpabc5
Molecule annotation
1
DNA-directed RNA Polymerase II Subunit Rpb11
Molecule annotation
1
DNA-directed RNA Polymerases I, II, and III Subunit Rpabc4
Molecule annotation
1
Amatoxin
Molecule annotation
Nucleotides(3 molecules)
1
5'-d(*ap*ap*ap*cp*tp*ap*cp*tp*tp*gp *ap*gp*cp*t)-3'
Molecule annotation
1
5'-r(*ap*ap*ap*gp*ap*cp*cp*ap*gp*gp*c)-3'
Molecule annotation
1
5'-d(*ap*gp*cp*tp*cp*ap*ap*gp*tp*ap *gp*tp*tp*ap*cp*gp*cp*cp*brup*gp*gp*tp*cp*ap*tp*t)-3'
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
8
ZINC IONZINC ION
2
1
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303