2VX3: Crystal structure of the human dual specificity tyrosine- phosphorylation-regulated kinase 1A

PDB ID: 2VX3Download
MMDB ID: 66700
PDB Deposition Date: 2008/6/30
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.4  Å
Source Organism:
Similar Structures:
Biological Unit for 2VX3: monomeric; determined by author and by software (PISA)
Molecular Components in 2VX3
Label Count Molecule
Protein (1 molecule)
1
Dual Specificity Tyrosine-phosphorylation- Regulated Kinase 1A
(Gene symbol: DYRK1A)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
N-(5-{[(2S)-4-amino-2-(3-chlorophenyl)butanoyl]amino}-1H-indazol-3-yl)benzamideN-(5-{[(2S)-4-amino-2-(3-chlorophenyl)butanoyl]amino}-1H-indazol-3-yl)benzamide
2
1
CHLORIDE IONCHLORIDE ION
3
3
HEXAETHYLENE GLYCOLHEXAETHYLENE GLYCOL
4
1
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303