2W97: Crystal Structure of eIF4E Bound to Glycerol and eIF4G1 peptide

PDB ID: 2W97Download
MMDB ID: 81043
PDB Deposition Date: 2009/1/22
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.29  Å
Source Organism:
Similar Structures:
Biological Unit for 2W97: tetrameric; determined by author and by software (PQS)
Molecular Components in 2W97
Label Count Molecule
Proteins (4 molecules)
1
Eukaryotic Translation Initiation Factor 4E
(Gene symbol: EIF4E)
Molecule annotation
1
Eukaryotic Translation Initiation Factor 4E
(Gene symbol: EIF4E)
Molecule annotation
2
Eukaryotic Translation Initiation Factor 4 Gamma 1
(Gene symbol: EIF4G1)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
1
[[(2R,3S,4R,5R)-5-(6-AMINO-3-METHYL-4-OXO-5H-IMIDAZO[4,5-C]PYRIDIN-1-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHOXY-HYDROXY-PHOSPHORYL] PHOSPHONO HYDROGEN PHOSPHATE[[(2R,3S,4R,5R)-5-(6-AMINO-3-METHYL-4-OXO-5H-IMIDAZO[4,5-C]PYRIDIN-1-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHOXY-HYDROXY-PHOSPHORYL] PHOSPHONO HYDROGEN PHOSPHATE
2
1
TRIETHYLENE GLYCOLTRIETHYLENE GLYCOL
3
4
SULFATE IONSULFATE ION
4
2
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303