2X7C: Crystal structure of human kinesin Eg5 in complex with (S)-enastron

PDB ID: 2X7CDownload
MMDB ID: 83264
PDB Deposition Date: 2010/2/26
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 2X7C: monomeric; determined by author and by software (PISA)
Molecular Components in 2X7C
Label Count Molecule
Protein (1 molecule)
1
Kinesin-like Protein Kif11
(Gene symbol: KIF11)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
ADENOSINE-5'-DIPHOSPHATEADENOSINE-5'-DIPHOSPHATE
2
1
MAGNESIUM IONMAGNESIUM ION
3
1
(S)-4-(3-HYDROXYPHENYL)-2-THIOXO-1,2,3,4,7,8-HEXAHYDROQUINAZOLIN-5(6H)-ONE(S)-4-(3-HYDROXYPHENYL)-2-THIOXO-1,2,3,4,7,8-HEXAHYDROQUINAZOLIN-5(6H)-ONE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303