2XN5: Crystal structure of thyroxine-binding globulin complexed with Furosemide

PDB ID: 2XN5Download
MMDB ID: 88624
PDB Deposition Date: 2010/7/30
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.7  Å
Source Organism:
Similar Structures:
Biological Unit for 2XN5: dimeric; determined by author and by software (PISA)
Molecular Components in 2XN5
Label Count Molecule
Proteins (2 molecules)
1
Thyroxine-binding Globulin
(Gene symbol: SERPINA7)
Molecule annotation
1
Thyroxine-binding Globulin
(Gene symbol: SERPINA7)
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
1
5-(AMINOSULFONYL)-4-CHLORO-2-[(2-FURYLMETHYL)AMINO]BENZOIC ACID5-(AMINOSULFONYL)-4-CHLORO-2-[(2-FURYLMETHYL)AMINO]BENZOIC ACID
2
4
CALCIUM IONCALCIUM ION
3
4
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303