2YHI: Trypanosoma brucei PTR1 in complex with inhibitor WH16

PDB ID: 2YHIDownload
MMDB ID: 240362
PDB Deposition Date: 2011/5/3
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 2YHI: tetrameric; determined by author and by software (PISA)
Molecular Components in 2YHI
Label Count Molecule
Proteins (4 molecules)
2
Pteridine Reductase, Putative
Molecule annotation
2
Pteridine Reductase, Putative
Molecule annotation
Chemicals and Non-standard biopolymers (14 molecules)
1
4
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
2
4
5-(2-CHLOROETHYL)-1,3,4-THIADIAZOL-2-AMINE5-(2-CHLOROETHYL)-1,3,4-THIADIAZOL-2-AMINE
3
1
(2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL(2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL
4
2
ACETATE IONACETATE ION
5
1
(2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL(2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL
6
2
2,3-DIHYDROXY-1,4-DITHIOBUTANE2,3-DIHYDROXY-1,4-DITHIOBUTANE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303