2Z7X: Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide

PDB ID: 2Z7XDownload
MMDB ID: 242512
PDB Deposition Date: 2007/8/29
Updated in MMDB: 2024/02
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 2Z7X: trimeric; determined by author and by software (PISA)
Molecular Components in 2Z7X
Label Count Molecule
Proteins (3 molecules)
1
Toll-like Receptor 2,variable Lymphocyte Receptor B
(Gene symbol: TLR2)
Molecule annotation
1
Toll-like Receptor 1,variable Lymphocyte Receptor B
(Gene symbol: TLR1)
Molecule annotation
1
Pam3csk4
Molecule annotation
Chemicals and Non-standard biopolymers (17 molecules)
1
10
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
2-acetamido-2-deoxy-alpha-D-glucopyranose2-acetamido-2-deoxy-alpha-D-glucopyranose
3
2
alpha-D-mannopyranosealpha-D-mannopyranose
4
2
beta-D-mannopyranosebeta-D-mannopyranose
5
1
PALMITIC ACIDPALMITIC ACID
6
1
(2S)-3-hydroxypropane-1,2-diyl dihexadecanoate(2S)-3-hydroxypropane-1,2-diyl dihexadecanoate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303