2ZM3: Complex Structure of Insulin-like Growth Factor Receptor and Isoquinolinedione Inhibitor

PDB ID: 2ZM3Download
MMDB ID: 64842
PDB Deposition Date: 2008/4/10
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.5  Å
Source Organism:
Similar Structures:
Biological Unit for 2ZM3: monomeric; determined by author
Molecular Components in 2ZM3
Label Count Molecule
Protein (1 molecule)
1
Insulin-like Growth Factor 1 Receptor
(Gene symbol: IGF1R)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(4Z)-6-bromo-4-({[4-(pyrrolidin-1-ylmethyl)phenyl]amino}methylidene)isoquinoline-1,3(2H,4H)-dione(4Z)-6-bromo-4-({[4-(pyrrolidin-1-ylmethyl)phenyl]amino}methylidene)isoquinoline-1,3(2H,4H)-dione
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303