3A4P: human c-MET kinase domain complexed with 6-benzyloxyquinoline inhibitor

PDB ID: 3A4PDownload
MMDB ID: 80075
PDB Deposition Date: 2009/7/13
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.54  Å
Source Organism:
Similar Structures:
Biological Unit for 3A4P: monomeric; determined by author and by software (PISA)
Molecular Components in 3A4P
Label Count Molecule
Protein (1 molecule)
1
Hepatocyte Growth Factor Receptor
(Gene symbol: MET)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
CHLORIDE IONCHLORIDE ION
2
2
ISOPROPYL ALCOHOLISOPROPYL ALCOHOL
3
1
(2E)-3-{6-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]quinolin-3-yl}-N-methylprop-2-enamide(2E)-3-{6-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]quinolin-3-yl}-N-methylprop-2-enamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303