3BBT: crystal structure of the ErbB4 kinase in complex with lapatinib

PDB ID: 3BBTDownload
MMDB ID: 62410
PDB Deposition Date: 2007/11/11
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 2.8  Å
Source Organism:
Similar Structures:
Biological Unit for 3BBT: monomeric; determined by software (PISA)
Molecular Components in 3BBT
Label Count Molecule
Protein (1 molecule)
1
Receptor Tyrosine-protein Kinase Erbb-4
(Gene symbol: ERBB4)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-{3-CHLORO-4-[(3-FLUOROBENZYL)OXY]PHENYL}-6-[5-({[2-(METHYLSULFONYL)ETHYL]AMINO}METHYL)-2-FURYL]-4-QUINAZOLINAMINEN-{3-CHLORO-4-[(3-FLUOROBENZYL)OXY]PHENYL}-6-[5-({[2-(METHYLSULFONYL)ETHYL]AMINO}METHYL)-2-FURYL]-4-QUINAZOLINAMINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303