3CQU: Crystal Structure of Akt-1 complexed with substrate peptide and inhibitor

PDB ID: 3CQUDownload
MMDB ID: 64701
PDB Deposition Date: 2008/4/3
Updated in MMDB: 2021/10
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
Similar Structures:
Biological Unit for 3CQU: dimeric; determined by author and by software (PISA)
Molecular Components in 3CQU
Label Count Molecule
Proteins (2 molecules)
1
Rac-alpha Serine/threonine-protein Kinase
(Gene symbol: AKT1)
Molecule annotation
1
Glycogen Synthase Kinase-3 Beta
(Gene symbol: GSK3B)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-[2-(5-methyl-4H-1,2,4-triazol-3-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amineN-[2-(5-methyl-4H-1,2,4-triazol-3-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303