3CWJ: Crystal structure of hcv ns5b polymerase with a novel pyridazinone inhibitor

PDB ID: 3CWJDownload
MMDB ID: 70977
PDB Deposition Date: 2008/4/21
Updated in MMDB: 2011/05
Experimental Method:
x-ray diffraction
Resolution: 2.4  Å
Source Organism:
Similar Structures:
Biological Unit for 3CWJ: monomeric; determined by author and by software (PISA)
Molecular Components in 3CWJ
Label Count Molecule
Protein (1 molecule)
1
RNA-directed RNA Polymerase
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-{3-[5-hydroxy-2-(3-methylbutyl)-3-oxo-6-thiophen-2-yl-2,3-dihydropyridazin-4-yl]-1,1-dioxido-2H-1,4-benzothiazin-7-yl}methanesulfonamideN-{3-[5-hydroxy-2-(3-methylbutyl)-3-oxo-6-thiophen-2-yl-2,3-dihydropyridazin-4-yl]-1,1-dioxido-2H-1,4-benzothiazin-7-yl}methanesulfonamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303