3DKF: Structure of MET receptor tyrosine kinase in complex with inhibitor SGX-523

PDB ID: 3DKFDownload
MMDB ID: 75103
PDB Deposition Date: 2008/6/24
Updated in MMDB: 2009/10
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 3DKF: monomeric; determined by author and by software (PISA)
Molecular Components in 3DKF
Label Count Molecule
Protein (1 molecule)
1
Hepatocyte Growth Factor Receptor
(Gene symbol: MET)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
CHLORIDE IONCHLORIDE ION
2
1
6-{[6-(1-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}quinoline6-{[6-(1-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}quinoline
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303