3DN5: Aldose Reductase in complex with novel biarylic inhibitor

PDB ID: 3DN5Download
MMDB ID: 70677
PDB Deposition Date: 2008/7/1
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.45  Å
Source Organism:
Similar Structures:
Biological Unit for 3DN5: monomeric; determined by author and by software (PISA)
Molecular Components in 3DN5
Label Count Molecule
Protein (1 molecule)
1
Aldose Reductase
(Gene symbol: AKR1B1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
2
1
3-[5-(3-nitrophenyl)thiophen-2-yl]propanoic acid3-[5-(3-nitrophenyl)thiophen-2-yl]propanoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303