3E30: Protein farnesyltransferase complexed with FPP and ethylene diamine inhibitor 4

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PDB ID: 3E30Download
MMDB ID: 70115
PDB Deposition Date: 2008/8/6
Updated in MMDB: 2011/05
Experimental Method:
x-ray diffraction
Resolution: 2.45  Å
Source Organism:
Similar Structures:
Biological Unit for 3E30: monomeric; determined by author
Molecular Graphic ?
3E30: Protein farnesyltransferase complexed with FPP and ethylene diamine inhibitor 4
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Interactions?
AA: Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha1FPP: FARNESYL DIPHOSPHATE2ED4: tert-butyl 4-({(2-{(4-cyanophenyl)[(1-methyl-1H-imidazol-5-yl)methyl]amino}ethyl)[(1-methyl-1H-imidazol-4-yl)sulfonyl]amino}methyl)piperidine-1-carboxylate
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Molecular Components in 3E30
Label Count Molecule
Protein (1 molecule)
1
Protein Farnesyltransferase/geranylgeranyltransferase Type-1 Subunit Alpha
(Gene symbol: Fnta)
1 Protein
SS Diagram
3D Domains
Domain Families
Super Families
175150225300377377 residues, click to see VAST similar structures.helix 94-109helix 114-126helix 131-144helix 148-161helix 167-179helix 186-195helix 200-213helix 219-229helix 234-246helix 253-269helix 275-284helix 295-302helix 309-325helix 330-346helix 353-366Domain 1 (1-146): click to see VAST similar structures1Domain 2 (147-216): click to see VAST similar structures2Domain 3 (217-289): click to see VAST similar structures3Domain 4 (290-377): click to see VAST similar structures4PLN02789 superfamilycl33568(64-365): farnesyltranstransferase
Chemicals and Non-standard biopolymers (2 molecules)
1
1
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