NCBI
National Center for
Biotechnology Information
Search
3E34:
Protein farnesyltransferase complexed with FPP and ethylenediamine-scaffold inhibitor 10
Citation is unavailable
PDB ID:
3E34
Download
MMDB ID:
70118
PDB Deposition Date:
2008/8/6
Updated in MMDB:
2011/05
Experimental Method:
x-ray diffraction
Resolution:
2.05 Å
Source Organism:
Rattus norvegicus
Similar Structures:
VAST+
Download sequence data
Default Biological Unit
All Biological Units (3)
Asymmetric Unit
Biological Unit for 3E34: monomeric; determined by author
Molecular Graphic
?
3D view
full-featured 3D viewer
Download Cn3D
Interactions
?
Download Stucture Data
?
Download
Format:
ASN.1 (Cn3D)
PDB
XML
JSON
PNG (image)
Data Set:
alpha-Carbons
Single 3D structure
* Mouse right-click to bring up context menu
Molecular Components in 3E34
Label
Count
Molecule
Protein (1 molecule)
A
1
Protein Farnesyltransferase/geranylgeranyltransferase Type-1 Subunit Alpha
(Gene symbol:
Fnta
)
1 Protein
SS Diagram
3D Domains
1
75
150
225
300
377
377 residues, click to see VAST similar structures.
helix 94-109
helix 114-126
helix 131-144
helix 148-161
helix 167-179
helix 186-195
helix 200-213
helix 219-229
helix 234-246
helix 253-269
helix 275-284
helix 295-302
helix 309-325
helix 330-346
helix 353-366
Domain 1 (1-146): click to see VAST similar structures
1
Domain 2 (147-216): click to see VAST similar structures
2
Domain 3 (217-289): click to see VAST similar structures
3
Domain 4 (290-377): click to see VAST similar structures
4
click domain graphic to toggle highlight of corresponding residues in 3D viewer
Chemicals and Non-standard biopolymers (2 molecules)
1
1
FARNESYL DIPHOSPHATE
2
1
3-{2'-[{[1-(tert-butoxycarbonyl)piperidin-4-yl]methyl}(2-{(4-cyanophenyl)[(1-methyl-1H-imidazol-5-yl)methyl]amino}ethyl)sulfamoyl]biphenyl-3-yl}propanoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303
You are here:
NCBI
>
Computational Biology Branch
>
Structure Group
> MMDB
Write to the Help Desk
HHS Vulnerability Disclosure