3E7B: Crystal Structure of Protein Phosphatase-1 Bound to the natural toxin inhibitor Tautomycin

PDB ID: 3E7BDownload
MMDB ID: 67773
PDB Deposition Date: 2008/8/18
Updated in MMDB: 2012/12
Experimental Method:
x-ray diffraction
Resolution: 1.7  Å
Source Organism:
Similar Structures:
Biological Unit for 3E7B: monomeric; determined by author and by software (PISA)
Molecular Components in 3E7B
Label Count Molecule
Protein (1 molecule)
1
Serine/threonine-protein Phosphatase Pp1-alpha Catalytic Subunit
(Gene symbol: PPP1CA)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
2
MANGANESE (II) IONMANGANESE (II) ION
2
1
(2Z)-2-[(1R)-3-{[(1R,2S,3R,6S,7S,10R)-10-{(2S,3S,6R,8S,9R)-3,9-dimethyl-8-[(3S)-3-methyl-4-oxopentyl]-1,7-dioxaspiro[5.5]undec-2-yl}-3,7-dihydroxy-2-methoxy-6-methyl-1-(1-methylethyl)-5-oxoundecyl]oxy}-1-hydroxy-3-oxopropyl]-3-methylbut-2-enedioic acid(2Z)-2-[(1R)-3-{[(1R,2S,3R,6S,7S,10R)-10-{(2S,3S,6R,8S,9R)-3,9-dimethyl-8-[(3S)-3-methyl-4-oxopentyl]-1,7-dioxaspiro[5.5]undec-2-yl}-3,7-dihydroxy-2-methoxy-6-methyl-1-(1-methylethyl)-5-oxoundecyl]oxy}-1-hydroxy-3-oxopropyl]-3-methylbut-2-enedioic acid
3
1
CHLORIDE IONCHLORIDE ION
4
1
GLYCEROLGLYCEROL
5
1
SODIUM IONSODIUM ION
6
4
AZIDE IONAZIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303