3EQC: X-ray structure of the human mitogen-activated protein kinase kinase 1 (MEK1) in a ternary complex with compound 1, ATP-GS AND MG2P

PDB ID: 3EQCDownload
MMDB ID: 69854
PDB Deposition Date: 2008/9/30
Updated in MMDB: 2012/12
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 3EQC: monomeric; determined by author and by software (PQS)
Molecular Components in 3EQC
Label Count Molecule
Protein (1 molecule)
1
Dual Specificity Mitogen-activated Protein Kinase Kinase 1
(Gene symbol: MAP2K1)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
2-[(2-chloro-4-iodophenyl)amino]-N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluorobenzamide2-[(2-chloro-4-iodophenyl)amino]-N-{[(2R)-2,3-dihydroxypropyl]oxy}-3,4-difluorobenzamide
2
1
PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTERPHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
3
1
MAGNESIUM IONMAGNESIUM ION
4
1
CALCIUM IONCALCIUM ION
5
1
SODIUM IONSODIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303