3EU5: Crystal structure of FTase(ALPHA-subunit; BETA-subunit DELTA C10) in complex with BiotinGPP

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PDB ID: 3EU5Download
MMDB ID: 75135
PDB Deposition Date: 2008/10/9
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.8  Å
Source Organism:
Similar Structures:
Biological Unit for 3EU5: dimeric; determined by author and by software (PISA)
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3EU5: Crystal structure of FTase(ALPHA-subunit; BETA-subunit DELTA C10) in complex with BiotinGPP
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Interactions?
AA: Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alphaBB: Protein farnesyltransferase subunit beta1ZN: ZINC ION2GBO: (2E,6E)-3,7-dimethyl-8-({5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}amino)octa-2,6-dien-1-yl trihydrogen diphosphate
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Data Set:
Molecular Components in 3EU5
Label Count Molecule
Proteins (2 molecules)
1
Protein Farnesyltransferase/geranylgeranyltransferase Type-1 Subunit Alpha
(Gene symbol: Fnta)
1 Protein
SS Diagram
3D Domains
175150225300377377 residues, click to see VAST similar structures.helix 94-109helix 114-126helix 131-144helix 149-161helix 167-179helix 186-195helix 200-213helix 219-229helix 234-247helix 253-269helix 275-284helix 295-302helix 309-325helix 330-346helix 353-366Domain 1 (1-146): click to see VAST similar structures1Domain 2 (147-216): click to see VAST similar structures2Domain 3 (217-289): click to see VAST similar structures3Domain 4 (290-377): click to see VAST similar structures4
1
Protein Farnesyltransferase Subunit Beta
(Gene symbol: Fntb)
1 Protein
SS Diagram
3D Domains
175150225300375427427 residues, click to see VAST similar structures.helix 43-63helix 75-87helix 100-114helix 120-132helix 151-163helix 174-183helix 202-214helix 249-262helix 270-279helix 308-318helix 332-341helix 360-373helix 405-416strand 133-136strand 138-141strand 184-187strand 189-192strand 232-235strand 237-240strand 343-346strand 348-351strand 374-379strand 380-385Domain 1 (70-183): click to see VAST similar structures1Domain 2 (184-325): click to see VAST similar structures2Domain 1 (326-395): click to see VAST similar structures1Domain 2 (396-427): click to see VAST similar structures2
Chemicals and Non-standard biopolymers (2 molecules)
1
1
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