3FYJ: Crystal structure of an optimzied benzothiophene inhibitor bound to MAPKAP Kinase-2 (MK-2)

PDB ID: 3FYJDownload
MMDB ID: 70714
PDB Deposition Date: 2009/1/22
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 3.8  Å
Source Organism:
Similar Structures:
Biological Unit for 3FYJ: monomeric; determined by author
Molecular Components in 3FYJ
Label Count Molecule
Protein (1 molecule)
1
MAP Kinase-activated Protein Kinase 2
(Gene symbol: MAPKAPK2)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(10R)-10-methyl-3-(6-methylpyridin-3-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one(10R)-10-methyl-3-(6-methylpyridin-3-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303