3H82: Crystal structure of the high affinity heterodimer of HIF2 alpha and ARNT C-terminal PAS domains with the artificial ligand THS020

PDB ID: 3H82Download
MMDB ID: 79223
PDB Deposition Date: 2009/4/28
Updated in MMDB: 2021/10
Experimental Method:
x-ray diffraction
Resolution: 1.5  Å
Source Organism:
Similar Structures:
Biological Unit for 3H82: dimeric; determined by author and by software (PISA)
Molecular Components in 3H82
Label Count Molecule
Proteins (2 molecules)
1
Aryl Hydrocarbon Receptor Nuclear Translocator
(Gene symbol: ARNT)
Molecule annotation
1
Endothelial PAS Domain-containing Protein 1
(Gene symbol: EPAS1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-(furan-2-ylmethyl)-2-nitro-4-(trifluoromethyl)anilineN-(furan-2-ylmethyl)-2-nitro-4-(trifluoromethyl)aniline
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303