3HY3: Structure of human MTHFS with 10-formyltetrahydrofolate

PDB ID: 3HY3Download
MMDB ID: 75346
PDB Deposition Date: 2009/6/22
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 3HY3: monomeric; determined by author and by software (PQS)
Molecular Components in 3HY3
Label Count Molecule
Protein (1 molecule)
1
5-formyltetrahydrofolate Cyclo-ligase
(Gene symbol: MTHFS)
Molecule annotation
Chemicals and Non-standard biopolymers (12 molecules)
1
1
N-({4-[{[(2R,4S,4aR,6S,8aS)-2-amino-4-hydroxydecahydropteridin-6-yl]methyl}(formyl)amino]phenyl}carbonyl)-D-glutamic acidN-({4-[{[(2R,4S,4aR,6S,8aS)-2-amino-4-hydroxydecahydropteridin-6-yl]methyl}(formyl)amino]phenyl}carbonyl)-D-glutamic acid
2
2
NICKEL (II) IONNICKEL (II) ION
3
9
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303