3I5N: Crystal structure of c-Met with triazolopyridazine inhibitor 13

PDB ID: 3I5NDownload
MMDB ID: 79253
PDB Deposition Date: 2009/7/6
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 3I5N: monomeric; determined by author and by software (PISA)
Molecular Components in 3I5N
Label Count Molecule
Protein (1 molecule)
1
Hepatocyte Growth Factor Receptor
(Gene symbol: MET)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
7-methoxy-N-[(6-phenyl[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl]-1,5-naphthyridin-4-amine7-methoxy-N-[(6-phenyl[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl]-1,5-naphthyridin-4-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303