3IJJ: Ternary Complex of Macrophage Migration Inhibitory Factor (MIF) Bound Both to 4-hydroxyphenylpyruvate and to the Allosteric Inhibitor AV1013 (R-stereoisomer)

PDB ID: 3IJJDownload
MMDB ID: 82752
PDB Deposition Date: 2009/8/4
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 1.25  Å
Source Organism:
Similar Structures:
Biological Unit for 3IJJ: trimeric; determined by author and by software (PISA)
Molecular Components in 3IJJ
Label Count Molecule
Proteins (3 molecules)
3
Macrophage Migration Inhibitory Factor
(Gene symbol: MIF)
Molecule annotation
Chemicals and Non-standard biopolymers (15 molecules)
1
3
(2E)-2-hydroxy-3-(4-hydroxyphenyl)prop-2-enoic acid(2E)-2-hydroxy-3-(4-hydroxyphenyl)prop-2-enoic acid
2
3
3-(4-HYDROXY-PHENYL)PYRUVIC ACID3-(4-HYDROXY-PHENYL)PYRUVIC ACID
3
8
CHLORIDE IONCHLORIDE ION
4
1
(2R)-2-amino-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]propan-1-one(2R)-2-amino-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]propan-1-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303