3K7W: Protein phosphatase 2A core complex bound to dinophysistoxin-2

PDB ID: 3K7WDownload
MMDB ID: 77886
PDB Deposition Date: 2009/10/13
Updated in MMDB: 2009/12
Experimental Method:
x-ray diffraction
Resolution: 2.96  Å
Source Organism:
Similar Structures:
Biological Unit for 3K7W: dimeric; determined by author and by software (PISA)
Molecular Components in 3K7W
Label Count Molecule
Proteins (2 molecules)
1
Serine/threonine-protein Phosphatase 2A 65 KDA Regulatory Subunit a Alpha Isoform
(Gene symbol: PPP2R1A)
Molecule annotation
1
Serine/threonine-protein Phosphatase 2A Catalytic Subunit Alpha Isoform
(Gene symbol: PPP2CA)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
3
SULFATE IONSULFATE ION
2
1
(2R)-2-hydroxy-3-[(2S,5R,6R,8S)-5-hydroxy-8-{(1R,2E)-3-[(2R,4a'R,5R,6'S,8'R,8a'S)-8'-hydroxy-6'-{(1S,3S)-1-hydroxy-3-[( 2S,6R,11S)-11-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl}-7'-methylideneoctahydro-3H,3'H-spiro[furan-2,2'-pyrano[3,2-b]p yran]-5-yl]-1-methylprop-2-en-1-yl}-10-methyl-1,7-dioxaspiro[5.5]undec-10-en-2-yl]-2-methylpropanoic acid(2R)-2-hydroxy-3-[(2S,5R,6R,8S)-5-hydroxy-8-{(1R,2E)-3-[(2R,4a'R,5R,6'S,8'R,8a'S)-8'-hydroxy-6'-{(1S,3S)-1-hydroxy-3-[( 2S,6R,11S)-11-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl}-7'-methylideneoctahydro-3H,3'H-spiro[furan-2,2'-pyrano[3,2-b]p yran]-5-yl]-1-methylprop-2-en-1-yl}-10-methyl-1,7-dioxaspiro[5.5]undec-10-en-2-yl]-2-methylpropanoic acid
3
2
MANGANESE (II) IONMANGANESE (II) ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303