3KCF: Crystal structure of TGFbRI complexed with a pyrazolone inhibitor

PDB ID: 3KCFDownload
MMDB ID: 78941
PDB Deposition Date: 2009/10/21
Updated in MMDB: 2009/12
Experimental Method:
x-ray diffraction
Resolution: 2.8  Å
Source Organism:
Similar Structures:
Biological Unit for 3KCF: monomeric; determined by author and by software (PISA)
Molecular Components in 3KCF
Label Count Molecule
Protein (1 molecule)
1
Tgf-beta Receptor Type-1
(Gene symbol: TGFBR1)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
4-[3-(methoxymethyl)phenyl]-1,2-dimethyl-5-quinoxalin-6-yl-1,2-dihydro-3H-pyrazol-3-one4-[3-(methoxymethyl)phenyl]-1,2-dimethyl-5-quinoxalin-6-yl-1,2-dihydro-3H-pyrazol-3-one
2
3
PHOSPHATE IONPHOSPHATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303