3KFA: Structural analysis of DFG-in and DFG-out dual Src-Abl inhibitors sharing a common vinyl purine template

PDB ID: 3KFADownload
MMDB ID: 78949
PDB Deposition Date: 2009/10/27
Updated in MMDB: 2009/12
Experimental Method:
x-ray diffraction
Resolution: 1.22  Å
Source Organism:
Similar Structures:
Biological Unit for 3KFA: monomeric; determined by author and by software (PISA)
Molecular Components in 3KFA
Label Count Molecule
Protein (1 molecule)
1
Tyrosine-protein Kinase Abl1
(Gene symbol: Abl1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
3-{(E)-2-[6-(cyclopropylamino)-9H-purin-9-yl]ethenyl}-4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]benzamide3-{(E)-2-[6-(cyclopropylamino)-9H-purin-9-yl]ethenyl}-4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]benzamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303