3NXU: Crystal structure of human cytochrome P4503A4 bound to an inhibitor ritonavir

PDB ID: 3NXUDownload
MMDB ID: 85615
PDB Deposition Date: 2010/7/14
Updated in MMDB: 2010/12
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 3NXU: monomeric; determined by author and by software (PISA)
Molecular Components in 3NXU
Label Count Molecule
Protein (1 molecule)
1
Cytochrome P450 3A4
(Gene symbol: CYP3A4)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
4
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
2
1
PROTOPORPHYRIN IX CONTAINING FEPROTOPORPHYRIN IX CONTAINING FE
3
1
RITONAVIRRITONAVIR
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303