3OG7: B-Raf Kinase V600E oncogenic mutant in complex with PLX4032

PDB ID: 3OG7Download
MMDB ID: 85076
PDB Deposition Date: 2010/8/16
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 2.45  Å
Source Organism:
Similar Structures:
Biological Unit for 3OG7: monomeric; determined by software (PISA)
Molecular Components in 3OG7
Label Count Molecule
Protein (1 molecule)
1
Akap9-braf Fusion Protein
(Gene symbol: BRAF)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-(3-{[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl}-2,4-difluorophenyl)propane-1-sulfonamideN-(3-{[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl}-2,4-difluorophenyl)propane-1-sulfonamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303