3OY3: Crystal structure of ABL T315I mutant kinase domain bound with a DFG-out inhibitor AP24589

PDB ID: 3OY3Download
MMDB ID: 87375
PDB Deposition Date: 2010/9/22
Updated in MMDB: 2010/12
Experimental Method:
x-ray diffraction
Resolution: 1.95  Å
Source Organism:
Similar Structures:
Biological Unit for 3OY3: monomeric; determined by author and by software (PISA)
Molecular Components in 3OY3
Label Count Molecule
Protein (1 molecule)
1
Tyrosine-protein Kinase Abl1
(Gene symbol: Abl1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
5-[(5-{[4-{[4-(2-hydroxyethyl)piperazin-1-yl]methyl}-3-(trifluoromethyl)phenyl]carbamoyl}-2-methylphenyl)ethynyl]-1-methyl-1H-imidazole-2-carboxamide5-[(5-{[4-{[4-(2-hydroxyethyl)piperazin-1-yl]methyl}-3-(trifluoromethyl)phenyl]carbamoyl}-2-methylphenyl)ethynyl]-1-methyl-1H-imidazole-2-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303