3R8D: Activation of the Human Nuclear Xenobiotic Receptor PXR by the Reverse Transcriptase-Targeted Anti-HIV Drug PNU-142721

PDB ID: 3R8DDownload
MMDB ID: 92743
PDB Deposition Date: 2011/3/23
Updated in MMDB: 2011/10
Experimental Method:
x-ray diffraction
Resolution: 2.8  Å
Source Organism:
Similar Structures:
Biological Unit for 3R8D: monomeric; determined by author and by software (PISA)
Molecular Components in 3R8D
Label Count Molecule
Protein (1 molecule)
1
Nuclear Receptor Subfamily 1 Group I Member 2
(Gene symbol: NR1I2)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
6-CHLORO-2-(1-FURO[2,3-C]PYRIDIN-5-YL-ETHYLSULFANYL)-PYRIMIDIN-4-YLAMINE6-CHLORO-2-(1-FURO[2,3-C]PYRIDIN-5-YL-ETHYLSULFANYL)-PYRIMIDIN-4-YLAMINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303