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3RTH:
Structure of Bace-1 (Beta-Secretase) in Complex with 6-(2-(3,3-Dimethylbut-1-ynyl)phenyl)quinolin-2-amine
PDB ID:
3RTH
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MMDB ID:
93310
PDB Deposition Date:
2011/5/3
Updated in MMDB:
2017/11
Experimental Method:
x-ray diffraction
Resolution:
2.7 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 3RTH: monomeric; determined by author and by software (PISA)
Molecular Components in 3RTH
Label
Count
Molecule
Protein (1 molecule)
A
1
Beta-secretase 1
(Gene symbol:
BACE1
)
Chemicals and Non-standard biopolymers (5 molecules)
1
4
IODIDE ION
2
1
6-[2-(3,3-dimethylbut-1-yn-1-yl)phenyl]quinolin-2-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303