3S7S: Crystal structure of human placental aromatase complexed with breast cancer drug exemestane

PDB ID: 3S7SDownload
MMDB ID: 100249
PDB Deposition Date: 2011/5/26
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 3.21  Å
Source Organism:
Similar Structures:
Biological Unit for 3S7S: monomeric; determined by author and by software (PISA)
Molecular Components in 3S7S
Label Count Molecule
Protein (1 molecule)
1
Cytochrome P450 19a1
(Gene symbol: CYP19A1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
PROTOPORPHYRIN IX CONTAINING FEPROTOPORPHYRIN IX CONTAINING FE
2
1
(8alpha,10alpha,13alpha)-6-methylideneandrosta-1,4-diene-3,17-dione(8alpha,10alpha,13alpha)-6-methylideneandrosta-1,4-diene-3,17-dione
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303