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3SKE:
I. Novel Hcv Ns5b Polymerase Inhibitors: Discovery Of Indole 2- Carboxylic Acids With C3-Heterocycles
PDB ID:
3SKE
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MMDB ID:
93339
PDB Deposition Date:
2011/6/22
Updated in MMDB:
2012/09
Experimental Method:
x-ray diffraction
Resolution:
1.97 Å
Source Organism:
Hepatitis C virus isolate HC-J4
Similar Structures:
VAST+
Download sequence data
Biological Unit for 3SKE: monomeric; determined by software (PISA)
Molecular Components in 3SKE
Label
Count
Molecule
Protein (1 molecule)
A
1
HCV Ns5b RNA_dependent RNA Polymerase
Chemicals and Non-standard biopolymers (2 molecules)
1
1
Phosphate Ion
2
1
1-[(2-Aminopyridin-4-Yl)methyl]-3-(2,4-Dioxo-1,2-Dihydrothieno[3,4-D]pyrimidin-3(4h)-Yl)-5-(Trifluoromethyl)-1h-Indole-2-Carboxylic Acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303