3SXR: Crystal structure of BMX non-receptor tyrosine kinase complex with dasatinib

PDB ID: 3SXRDownload
MMDB ID: 93769
PDB Deposition Date: 2011/7/15
Updated in MMDB: 2011/12
Experimental Method:
x-ray diffraction
Resolution: 2.4  Å
Source Organism:
Similar Structures:
Biological Unit for 3SXR: monomeric; determined by author
Molecular Components in 3SXR
Label Count Molecule
Protein (1 molecule)
1
Cytoplasmic Tyrosine-protein Kinase BMX
(Gene symbol: BMX)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDEN-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE
2
2
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303