3U88: Crystal structure of human menin in complex with MLL1 and LEDGF

PDB ID: 3U88Download
MMDB ID: 97290
PDB Deposition Date: 2011/10/16
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 3  Å
Source Organism:
Similar Structures:
Biological Unit for 3U88: trimeric; determined by author and by software (PISA)
Molecular Components in 3U88
Label Count Molecule
Proteins (3 molecules)
1
Menin
(Gene symbol: MEN1)
Molecule annotation
1
Histone-lysine N-methyltransferase 2A
(Gene symbol: KMT2A)
Molecule annotation
1
Lens Epithelium-derived Growth Factor
(Gene symbol: PSIP1)
Molecule annotation
Chemicals and Non-standard biopolymers (19 molecules)
1
2
CHOLIC ACIDCHOLIC ACID
2
4
L-CANAVANINEL-CANAVANINE
3
1
(4beta,8alpha,9R)-6'-methoxy-10,11-dihydrocinchonan-9-ol(4beta,8alpha,9R)-6'-methoxy-10,11-dihydrocinchonan-9-ol
4
6
GLYOXYLIC ACIDGLYOXYLIC ACID
5
6
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303