3WEF: Crystal structure of the human squalene synthase in complex with farnesyl thiopyrophosphate

PDB ID: 3WEFDownload
MMDB ID: 117375
PDB Deposition Date: 2013/7/7
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.35  Å
Source Organism:
Similar Structures:
Biological Unit for 3WEF: trimeric; determined by author and by software (PISA)
Molecular Components in 3WEF
Label Count Molecule
Proteins (3 molecules)
3
Squalene Synthase
(Gene symbol: FDFT1)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
5
S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATES-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303