4KP8: Crystal structure of catalytic domain of human carbonic anhydrase isozyme XII with 3-[(Pyrimidin-2-ylsulfanyl)acetyl]benzenesulfonamide

PDB ID: 4KP8Download
MMDB ID: 114898
PDB Deposition Date: 2013/5/13
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 4KP8: dimeric; determined by author
Molecular Components in 4KP8
Label Count Molecule
Proteins (2 molecules)
2
Carbonic Anhydrase 12
(Gene symbol: CA12)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
2
ZINC IONZINC ION
2
2
3-[(pyrimidin-2-ylsulfanyl)acetyl]benzenesulfonamide3-[(pyrimidin-2-ylsulfanyl)acetyl]benzenesulfonamide
3
1
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
4
1
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
5
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303