4NGE: Crystal Structure of Human Presequence Protease in Complex with Amyloid-beta (1-40)

PDB ID: 4NGEDownload
MMDB ID: 168793
PDB Deposition Date: 2013/11/1
Updated in MMDB: 2018/11
Experimental Method:
x-ray diffraction
Resolution: 2.704  Å
Source Organism:
Similar Structures:
Biological Unit for 4NGE: trimeric; determined by author
Molecular Components in 4NGE
Label Count Molecule
Proteins (3 molecules)
1
Presequence Protease, Mitochondrial
(Gene symbol: PITRM1)
Molecule annotation
1
Beta-amyloid Protein 40
(Gene symbol: APP)
Molecule annotation
1
Beta-amyloid Protein 40
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
ZINC IONZINC ION
2
1
GLYCEROLGLYCEROL
3
2
ACETATE IONACETATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303