4QJ0: Crystal structure of catalytic domain of human carbonic anhydrase isozyme XII with inhibitor

PDB ID: 4QJ0Download
MMDB ID: 128571
PDB Deposition Date: 2014/6/3
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.55  Å
Source Organism:
Similar Structures:
Biological Unit for 4QJ0: dimeric; determined by author
Molecular Components in 4QJ0
Label Count Molecule
Proteins (2 molecules)
2
Carbonic Anhydrase 12
(Gene symbol: CA12)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
ZINC IONZINC ION
2
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
2
2,3,6-trifluoro-5-{[(1R,2S)-2-hydroxy-1,2-diphenylethyl]amino}-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide2,3,6-trifluoro-5-{[(1R,2S)-2-hydroxy-1,2-diphenylethyl]amino}-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303