4QX5: Neutron diffraction reveals hydrogen bonds critical for cGMP-selective activation: Insights for PKG agonist design

PDB ID: 4QX5Download
MMDB ID: 124679
PDB Deposition Date: 2014/7/18
Updated in MMDB: 2017/12
Experimental Method:
x-ray diffraction
Resolution: 1.318  Å
Source Organism:
Similar Structures:
Biological Unit for 4QX5: monomeric; determined by author and by software (PISA)
Molecular Components in 4QX5
Label Count Molecule
Protein (1 molecule)
1
Cgmp-dependent Protein Kinase 1
(Gene symbol: PRKG1)
Molecule annotation
Chemicals and Non-standard biopolymers (19 molecules)
1
1
ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATEADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE
2
18
IODIDE IONIODIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303