4RLO: Human p70s6k1 with ruthenium-based inhibitor EM5

PDB ID: 4RLODownload
MMDB ID: 126312
PDB Deposition Date: 2014/10/17
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 2.527  Å
Source Organism:
Similar Structures:
Biological Unit for 4RLO: monomeric; determined by author
Molecular Components in 4RLO
Label Count Molecule
Protein (1 molecule)
1
Ribosomal Protein S6 Kinase Beta-1
(Gene symbol: RPS6KB1)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
[(amino-kappaN)methanethiolato](3-fluoro-9-hydroxypyrido[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H,12H)-dionato-kappa~2~N,N')(1,4,7-trithionane-kappa~3~S~1~,S~4~,S~7~)ruthenium[(amino-kappaN)methanethiolato](3-fluoro-9-hydroxypyrido[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H,12H)-dionato-kappa~2~N,N')(1,4,7-trithionane-kappa~3~S~1~,S~4~,S~7~)ruthenium
2
1
GLYCEROLGLYCEROL
3
3
CHLORIDE IONCHLORIDE ION
4
1
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303