4U45: MAP4K4 in complex with inhibitor (compound 25)

PDB ID: 4U45Download
MMDB ID: 122940
PDB Deposition Date: 2014/7/23
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.58  Å
Source Organism:
Similar Structures:
Biological Unit for 4U45: dimeric; determined by author and by software (PISA)
Molecular Components in 4U45
Label Count Molecule
Proteins (2 molecules)
2
Mitogen-activated Protein Kinase Kinase Kinase Kinase 4
(Gene symbol: MAP4K4)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
MAGNESIUM IONMAGNESIUM ION
2
1
6-(1H-pyrazol-4-yl)-N-(pyridin-4-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine6-(1H-pyrazol-4-yl)-N-(pyridin-4-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine
3
1
2-(N-MORPHOLINO)-ETHANESULFONIC ACID2-(N-MORPHOLINO)-ETHANESULFONIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303