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4V1M:
Architecture of the RNA polymerase II-Mediator core transcription initiation complex
PDB ID:
4V1M
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MMDB ID:
126744
PDB Deposition Date:
2014/9/29
Updated in MMDB:
2015/09
Experimental Method:
electron microscopy
Resolution:
6.6 Å
Source Organism:
synthetic construct
▼
Taxonomy
Molecule
synthetic construct
N, P, T
Saccharomyces cerevisiae
A, B, C, E, F, H, I, J, K, L
Similar Structures:
VAST+
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Biological Unit for 4V1M: tridecameric; determined by author
Molecular Components in 4V1M
Label
Count
Molecule
Proteins (10 molecules)
A
1
DNA-directed RNA Polymerase II Subunit Rpb1
B
1
DNA-directed RNA Polymerase II Subunit Rpb2
C
1
DNA-directed RNA Polymerase II Subunit Rpb3
E
1
DNA-directed RNA Polymerases I, II, and III Subunit Rpabc 1
F
1
DNA-directed RNA Polymerases I, II, and III Subunit Rpabc 2
H
1
DNA-directed RNA Polymerases I, II, and III Subunit Rpabc 3
I
1
DNA-directed RNA Polymerase II Subunit Rpb9
J
1
DNA-directed RNA Polymerases I, II, and III Subunit Rpabc 5
K
1
DNA-directed RNA Polymerase II Subunit Rpb11
L
1
DNA-directed RNA Polymerases I, II, and III Subunit Rpabc 4
Nucleotides(3 molecules)
N
1
5'-d(*ap*ap*gp*tp*ap*cp*tp*tp*gp*ap)-3'
P
1
5'-d(*cp*cp*ap*gp*gp*ap)-3'
T
1
5'-d(*tp*cp*ap*ap*gp*tp*ap*cp*tp*tp*tp*tp*tp*cp *cp*brup*gp*gp*tp*c)-3'
Chemicals and Non-standard biopolymers (9 molecules)
1
8
ZINC ION
2
1
MAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303