4W5R: The Crystal Structure of Human Argonaute2 Bound to a Guide and Target RNA Containing Seed Pairing from 2-8 (Long Target)

PDB ID: 4W5RDownload
MMDB ID: 124745
PDB Deposition Date: 2014/8/18
Updated in MMDB: 2017/12
Experimental Method:
x-ray diffraction
Resolution: 2.5  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 4W5R: trimeric; determined by author and by software (PISA)
Molecular Components in 4W5R
Label Count Molecule
Protein (1 molecule)
1
Protein Argonaute-2
Molecule annotation
Nucleotides(2 molecules)
1
RNA (5'-r(p*up*up*cp*ap*cp*ap*up*up*gp*up*u)-3')
Molecule annotation
1
RNA (5'-r(p*ap*ap*up*gp*up*gp*ap*ap*a)-3')
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
2
ISOPROPYL ALCOHOLISOPROPYL ALCOHOL
2
3
PHENOLPHENOL
3
2
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303