4X8C: Crystal structure of human peptidylarginine deiminase type4 (PAD4) in complex with GSK147

PDB ID: 4X8CDownload
MMDB ID: 126543
PDB Deposition Date: 2014/12/10
Updated in MMDB: 2017/12
Experimental Method:
x-ray diffraction
Resolution: 3.1  Å
Source Organism:
Similar Structures:
Biological Unit for 4X8C: dimeric; determined by author and by software (PISA)
Molecular Components in 4X8C
Label Count Molecule
Proteins (2 molecules)
2
Protein-arginine Deiminase Type-4
(Gene symbol: PADI4)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
4
CALCIUM IONCALCIUM ION
2
2
[(3S,4R)-3-amino-4-hydroxypiperidin-1-yl]{2-[1-(cyclopropylmethyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-7-methoxy-1-methyl-1H-benzimidazol-5-yl}methanone[(3S,4R)-3-amino-4-hydroxypiperidin-1-yl]{2-[1-(cyclopropylmethyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-7-methoxy-1-methyl-1H-benzimidazol-5-yl}methanone
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303