4YLJ: Crystal structure of DYRK1A in complex with 10-Iodo-substituted 11H-indolo[3,2-c]quinoline-6-carboxylic acid inhibitor 5j

PDB ID: 4YLJDownload
MMDB ID: 128150
PDB Deposition Date: 2015/3/5
Updated in MMDB: 2017/12
Experimental Method:
x-ray diffraction
Resolution: 2.58  Å
Source Organism:
Similar Structures:
Biological Unit for 4YLJ: monomeric; determined by author
Molecular Components in 4YLJ
Label Count Molecule
Protein (1 molecule)
1
Dual Specificity Tyrosine-phosphorylation-regulated Kinase 1A
(Gene symbol: DYRK1A)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
2
TETRAETHYLENE GLYCOLTETRAETHYLENE GLYCOL
2
2
SULFATE IONSULFATE ION
3
1
10-iodo-11H-indolo[3,2-c]quinoline-6-carboxylic acid10-iodo-11H-indolo[3,2-c]quinoline-6-carboxylic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303