5C4G: Crystal structure of an engineered construct of phosphatidylinositol 4 kinase III beta with the inhibitor BQR695 in complex with GDP loaded Rab11

PDB ID: 5C4GDownload
MMDB ID: 135713
PDB Deposition Date: 2015/6/18
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 3.2  Å
Source Organism:
Similar Structures:
Biological Unit for 5C4G: dimeric; determined by author and by software (PISA)
Molecular Components in 5C4G
Label Count Molecule
Proteins (2 molecules)
1
Ras-related Protein Rab-11a
(Gene symbol: RAB11A)
Molecule annotation
1
Phosphatidylinositol 4-kinase Beta
(Gene symbol: PI4KB)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
MAGNESIUM IONMAGNESIUM ION
2
1
GUANOSINE-5'-DIPHOSPHATEGUANOSINE-5'-DIPHOSPHATE
3
2
SULFATE IONSULFATE ION
4
1
N~2~-[7-(3,4-dimethoxyphenyl)quinoxalin-2-yl]-N-methylglycinamideN~2~-[7-(3,4-dimethoxyphenyl)quinoxalin-2-yl]-N-methylglycinamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303